Recent Research Publications

Stay updated with our latest research findings.

Norvil AB*, Petell CJ**, Alabdi LA**, Wu L*, Rossie S, Gowher H. Dnmt3b methylates DNA by a non-cooperative mechanism and its activity is unaffected by manipulations at the predicted dimer interface. Biochemistry 2016 Nov 4th. Impact Factor: 3.0

Norvil AB**, AlAbdi L**, Liu B***, Forstoffer NE*, Michie AR*, Chen T, Gowher H. The Acute Myeloid Leukemia variant DNMT3A Arg882His is a DNMT3B-like enzyme. Nucleic Acids Res. 2020 Apr 17;48(7):3761-3775. Impact Factor: 11.2

AlAbdi L**, Saha D***, He M***, Dar MS***, Utturkar SM, Sudyanti PA**, McCune S*, Spears BH*, Breedlove JA*, Lanman NA, Gowher H. Oct4 mediated inhibition of Lsd1 activity promotes the active and primed state of pluripotency enhancers. 2020 Cell Reports 30 (5), 1478-1490. Impact Factor: 7.8

Norvil AB**, Saha D***, Saleem Dar M***, Gowher H. Effect of Disease-Associated Germline Mutations on Structure Function Relationship of DNA Methyltransferases. Genes (Basel). 2019 May 14;10(5).Impact Factor: 3.3

Alabdi, LA **, He M, Yang Q***, Norvil, AB** and Gowher H. The transcription factor Vezf1 represses the expression of the antiangiogenic factor Cited2 in endothelial cells. J Biol Chem. 2018 Jul 13;293 (28):11109-11118. Impact Factor: 4.1